Cargando…
p21 promotes oncolytic adenoviral activity in ovarian cancer and is a potential biomarker
The oncolytic adenovirus dl922-947 replicates selectively within and lyses cells with a dysregulated Rb pathway, a finding seen in > 90% human cancers. dl922-947 is more potent than wild type adenovirus and the E1B-deletion mutant dl1520 (Onyx-015). We wished to determine which host cell factors...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904726/ https://www.ncbi.nlm.nih.gov/pubmed/20598155 http://dx.doi.org/10.1186/1476-4598-9-175 |