Sampling the Solution Space in Genome-Scale Metabolic Networks Reveals Transcriptional Regulation in Key Enzymes

Genome-scale metabolic models are available for an increasing number of organisms and can be used to define the region of feasible metabolic flux distributions. In this work we use as constraints a small set of experimental metabolic fluxes, which reduces the region of feasible metabolic states. Onc...

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Detalles Bibliográficos
Autores principales: Bordel, Sergio, Agren, Rasmus, Nielsen, Jens
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904763/
https://www.ncbi.nlm.nih.gov/pubmed/20657658
http://dx.doi.org/10.1371/journal.pcbi.1000859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904763/
https://www.ncbi.nlm.nih.gov/pubmed/20657658
http://dx.doi.org/10.1371/journal.pcbi.1000859

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