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Organization of Cellular Receptors into a Nanoscale Junction during HIV-1 Adhesion

The fusion of the human immunodeficiency virus type 1 (HIV-1) with its host cell is the target for new antiretroviral therapies. Viral particles interact with the flexible plasma membrane via viral surface protein gp120 which binds its primary cellular receptor CD4 and subsequently the coreceptor CC...

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Detalles Bibliográficos
Autores principales: Dobrowsky, Terrence M., Daniels, Brian R., Siliciano, Robert F., Sun, Sean X., Wirtz, Denis
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904768/
https://www.ncbi.nlm.nih.gov/pubmed/20657663
http://dx.doi.org/10.1371/journal.pcbi.1000855