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Hepatitis B Virus Polymerase Blocks Pattern Recognition Receptor Signaling via Interaction with DDX3: Implications for Immune Evasion

Viral infection leads to induction of pattern-recognition receptor signaling, which leads to interferon regulatory factor (IRF) activation and ultimately interferon (IFN) production. To establish infection, many viruses have strategies to evade the innate immunity. For the hepatitis B virus (HBV), w...

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Detalles Bibliográficos
Autores principales: Wang, Haifeng, Ryu, Wang-Shick
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904777/
https://www.ncbi.nlm.nih.gov/pubmed/20657822
http://dx.doi.org/10.1371/journal.ppat.1000986