Extreme CD8 T Cell Requirements for Anti-Malarial Liver-Stage Immunity following Immunization with Radiation Attenuated Sporozoites

Radiation-attenuated Plasmodium sporozoites (RAS) are the only vaccine shown to induce sterilizing protection against malaria in both humans and rodents. Importantly, these “whole-parasite” vaccines are currently under evaluation in human clinical trials. Studies with inbred mice reveal that RAS-ind...

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Detalles Bibliográficos
Autores principales: Schmidt, Nathan W., Butler, Noah S., Badovinac, Vladimir P., Harty, John T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904779/
https://www.ncbi.nlm.nih.gov/pubmed/20657824
http://dx.doi.org/10.1371/journal.ppat.1000998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904779/
https://www.ncbi.nlm.nih.gov/pubmed/20657824
http://dx.doi.org/10.1371/journal.ppat.1000998

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