Cargando…

Extreme CD8 T Cell Requirements for Anti-Malarial Liver-Stage Immunity following Immunization with Radiation Attenuated Sporozoites

Radiation-attenuated Plasmodium sporozoites (RAS) are the only vaccine shown to induce sterilizing protection against malaria in both humans and rodents. Importantly, these “whole-parasite” vaccines are currently under evaluation in human clinical trials. Studies with inbred mice reveal that RAS-ind...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schmidt, Nathan W., Butler, Noah S., Badovinac, Vladimir P., Harty, John T.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904779/ https://www.ncbi.nlm.nih.gov/pubmed/20657824 http://dx.doi.org/10.1371/journal.ppat.1000998

Ejemplares similares

Varying Immunizations With Plasmodium Radiation-Attenuated Sporozoites Alter Tissue-Specific CD8(+) T Cell Dynamics
por: Frank, Roland, et al.
Publicado: (2018)

Protective CD8+ T lymphocytes in Primates Immunized with Malaria Sporozoites
por: Weiss, Walter R., et al.
Publicado: (2012)

Immunization with Radiation-Attenuated Plasmodium berghei Sporozoites Induces Liver cCD8α(+)DC that Activate CD8(+)T Cells against Liver-Stage Malaria
por: Jobe, Ousman, et al.
Publicado: (2009)

IMRAS—Immunization with radiation-attenuated Plasmodium falciparum sporozoites by mosquito bite: Cellular immunity to sporozoites, CSP, AMA1, TRAP and CelTOS
por: Sedegah, Martha, et al.
Publicado: (2021)

Intradermal immunization of mice with radiation-attenuated sporozoites of Plasmodium yoelii induces effective protective immunity
por: Voza, Tatiana, et al.
Publicado: (2010)

Strain-Specific Protective Effect of the Immunity Induced by Live Malarial Sporozoites under Chloroquine Cover
por: Wijayalath, Wathsala, et al.
Publicado: (2012)

Novel ELISA method as exploratory tool to assess immunity induced by radiated attenuated sporozoites to decipher protective immunity
por: Knepper, Trey A., et al.
Publicado: (2017)

Longitudinal immune profiling after radiation-attenuated sporozoite vaccination reveals coordinated immune processes correlated with malaria protection
por: Duffy, Fergal J., et al.
Publicado: (2022)

Predicting CD62L expression during the CD8+ T cell response in vivo
por: Schlub, Timothy E., et al.
Publicado: (2009)

Differential Role of “Signal 3” Inflammatory Cytokines in Regulating CD8 T Cell Expansion and Differentiation in vivo
por: Pham, Nhat-Long L., et al.
Publicado: (2011)

Kinetics of Mosquito-Injected Plasmodium Sporozoites in Mice: Fewer Sporozoites Are Injected into Sporozoite-Immunized Mice
por: Kebaier, Chahnaz, et al.
Publicado: (2009)

MAEBL Is Essential for Malarial Sporozoite Infection of the Mosquito Salivary Gland
por: Kariu, Tohru, et al.
Publicado: (2002)

Diverse CD8 T Cell Responses to Viral Infection Revealed by the Collaborative Cross
por: Martin, Matthew D., et al.
Publicado: (2020)

Mosquito bite immunization with radiation-attenuated Plasmodium falciparum sporozoites: safety, tolerability, protective efficacy and humoral immunogenicity
por: Hickey, Bradley W., et al.
Publicado: (2016)

Unique transcriptional profile of liver-resident memory CD8(+) T cells induced by immunization with malaria sporozoites
por: Tse, Sze-Wah, et al.
Publicado: (2013)

Defining rules of CD8(+) T cell expansion against pre-erythrocytic Plasmodium antigens in sporozoite-immunized mice
por: Billman, Zachary P., et al.
Publicado: (2016)

Immunization with genetically attenuated P52-deficient Plasmodium berghei sporozoites induces a long-lasting effector memory CD8(+ )T cell response in the liver
por: Douradinha, Bruno, et al.
Publicado: (2011)

Inflammation Controls Susceptibility of Immune-Experienced Mice to Sepsis
por: Berton, Roger R., et al.
Publicado: (2022)

A malarial cysteine protease is necessary for Plasmodium sporozoite egress from oocysts
por: Aly, Ahmed S.I., et al.
Publicado: (2005)

Phenotypic characterization of Plasmodium berghei responsive CD8+ T cells after immunization with live sporozoites under chloroquine cover
por: Brando, Clara, et al.
Publicado: (2014)

Cryopreservation of Plasmodium Sporozoites
por: Bowers, Carson, et al.
Publicado: (2022)

Revealing the Complexity in CD8 T Cell Responses to Infection in Inbred C57B/6 versus Outbred Swiss Mice
por: Martin, Matthew D., et al.
Publicado: (2017)

Phenotypic and Functional Alterations in Circulating Memory CD8 T Cells with Time after Primary Infection
por: Martin, Matthew D., et al.
Publicado: (2015)

The Timing of Stimulation and IL-2 Signaling Regulate Secondary CD8 T Cell Responses
por: Khan, Shaniya H., et al.
Publicado: (2015)

Defining Memory CD8 T Cell
por: Martin, Matthew D., et al.
Publicado: (2018)

Antigen Exposure History Defines CD8 T Cell Dynamics and Protection during Localized Pulmonary Infections
por: Van Braeckel-Budimir, Natalija, et al.
Publicado: (2017)

Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria
por: Watson, Felicia N, et al.
Publicado: (2023)

Progress with PfSPZ Vaccine, a radiation attenuated Plasmodium falciparum sporozoite vaccine
por: Billingsley, Peter, et al.
Publicado: (2014)

Quantification of wild-type and radiation attenuated Plasmodium falciparum sporozoite motility in human skin
por: Winkel, Béatrice M. F., et al.
Publicado: (2019)

Species-specific escape of Plasmodium sporozoites from oocysts of avian, rodent, and human malarial parasites
por: Orfano, Alessandra S., et al.
Publicado: (2016)

Circumsporozoite Protein-Specific K(d)-Restricted CD8+ T Cells Mediate Protective Antimalaria Immunity in Sporozoite-Immunized MHC-I-K(d) Transgenic Mice
por: Huang, Jing, et al.
Publicado: (2014)

Blood-stage immunity to Plasmodium chabaudi malaria following chemoprophylaxis and sporozoite immunization
por: Nahrendorf, Wiebke, et al.
Publicado: (2015)

Protective function and durability of mouse lymph node-resident memory CD8(+) T cells
por: Anthony, Scott M, et al.
Publicado: (2021)

Peripherally induced brain tissue-resident memory CD8(+) T cells mediate protection against CNS infection
por: Urban, Stina L., et al.
Publicado: (2020)

Systems analysis of immune responses to attenuated P. falciparum malaria sporozoite vaccination reveals excessive inflammatory signatures correlating with impaired immunity
por: Du, Ying, et al.
Publicado: (2022)

Sepsis leads to lasting changes in phenotype and function of naïve CD8 T cells
por: Berton, Roger R., et al.
Publicado: (2023)

IMRAS—A clinical trial of mosquito-bite immunization with live, radiation-attenuated P. falciparum sporozoites: Impact of immunization parameters on protective efficacy and generation of a repository of immunologic reagents
por: Hickey, Bradley, et al.
Publicado: (2020)

Long Term Protection after Immunization with P. berghei Sporozoites Correlates with Sustained IFNγ Responses of Hepatic CD8+ Memory T Cells
por: Nganou-Makamdop, Krystelle, et al.
Publicado: (2012)

In vivo CD8+ T Cell Dynamics in the Liver of Plasmodium yoelii Immunized and Infected Mice
por: Cabrera, Mynthia, et al.
Publicado: (2013)

Chemoprophylaxis with sporozoite immunization in P. knowlesi rhesus monkeys confers protection and elicits sporozoite-specific memory T cells in the liver
por: Pichyangkul, Sathit, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_92i6l4h153kkeghrhvi89es82s