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Importance of polyadenylation in the selective elimination of meiotic mRNAs in growing S. pombe cells

A number of meiosis-specific mRNAs are initially weakly transcribed, but then selectively removed during fission yeast mitotic growth. These mRNAs harbour a region termed DSR (determinant of selective removal), which is recognized by the YTH family RNA-binding protein Mmi1p. Mmi1p directs the destru...

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Detalles Bibliográficos
Autores principales: Yamanaka, Soichiro, Yamashita, Akira, Harigaya, Yuriko, Iwata, Ryo, Yamamoto, Masayuki
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905246/
https://www.ncbi.nlm.nih.gov/pubmed/20512112
http://dx.doi.org/10.1038/emboj.2010.108