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The Runx transcriptional co-activator, CBFβ, is essential for invasion of breast cancer cells

BACKGROUND: The transcription factor Runx2 has an established role in cancers that metastasize to bone. In metastatic breast cancer cells Runx2 is overexpressed and contributes to the invasive capacity of the cells by regulating the expression of several invasion genes. CBFβ is a transcriptional co-...

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Detalles Bibliográficos
Autores principales: Mendoza-Villanueva, Daniel, Deng, Wensheng, Lopez-Camacho, Cesar, Shore, Paul
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905338/
https://www.ncbi.nlm.nih.gov/pubmed/20591170
http://dx.doi.org/10.1186/1476-4598-9-171