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The Runx transcriptional co-activator, CBFβ, is essential for invasion of breast cancer cells
BACKGROUND: The transcription factor Runx2 has an established role in cancers that metastasize to bone. In metastatic breast cancer cells Runx2 is overexpressed and contributes to the invasive capacity of the cells by regulating the expression of several invasion genes. CBFβ is a transcriptional co-...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905338/ https://www.ncbi.nlm.nih.gov/pubmed/20591170 http://dx.doi.org/10.1186/1476-4598-9-171 |