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Gelsolin Plays a Role in the Actin Polymerization Complex of Hair Cell Stereocilia

A complex of proteins scaffolded by the PDZ protein, whirlin, reside at the stereocilia tip and are critical for stereocilia development and elongation. We have shown that in outer hair cells (OHCs) whirlin is part of a larger complex involving the MAGUK protein, p55, and protein 4.1R. Whirlin inter...

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Detalles Bibliográficos
Autores principales: Mburu, Philomena, Romero, María Rosario, Hilton, Helen, Parker, Andrew, Townsend, Stuart, Kikkawa, Yoshiaki, Brown, Steve D. M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905391/
https://www.ncbi.nlm.nih.gov/pubmed/20661277
http://dx.doi.org/10.1371/journal.pone.0011627