Cargando…

Inhibition of Iron Uptake Is Responsible for Differential Sensitivity to V-ATPase Inhibitors in Several Cancer Cell Lines

Many cell lines derived from tumors as well as transformed cell lines are far more sensitive to V-ATPase inhibitors than normal counterparts. The molecular mechanisms underlying these differences in sensitivity are not known. Using global gene expression data, we show that the most sensitive respons...

Descripción completa

Detalles Bibliográficos
Autores principales: Straud, Sarah, Zubovych, Iryna, De Brabander, Jef K., Roth, Michael G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905441/
https://www.ncbi.nlm.nih.gov/pubmed/20661293
http://dx.doi.org/10.1371/journal.pone.0011629