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Inhibition of Iron Uptake Is Responsible for Differential Sensitivity to V-ATPase Inhibitors in Several Cancer Cell Lines
Many cell lines derived from tumors as well as transformed cell lines are far more sensitive to V-ATPase inhibitors than normal counterparts. The molecular mechanisms underlying these differences in sensitivity are not known. Using global gene expression data, we show that the most sensitive respons...
Autores principales: | Straud, Sarah, Zubovych, Iryna, De Brabander, Jef K., Roth, Michael G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905441/ https://www.ncbi.nlm.nih.gov/pubmed/20661293 http://dx.doi.org/10.1371/journal.pone.0011629 |
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