Cargando…

An alignment algorithm for bisulfite sequencing using the Applied Biosystems SOLiD System

Summary: Bisulfite sequencing allows cytosine methylation, an important epigenetic marker, to be detected via nucleotide substitutions. Since the Applied Biosystems SOLiD System uses a unique di-base encoding that increases confidence in the detection of nucleotide substitutions, it is a potentially...

Descripción completa

Detalles Bibliográficos
Autores principales: Ondov, Brian D., Cochran, Charles, Landers, Mark, Meredith, Gavin D., Dudas, Miroslav, Bergman, Nicholas H.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905549/
https://www.ncbi.nlm.nih.gov/pubmed/20562417
http://dx.doi.org/10.1093/bioinformatics/btq291