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An alignment algorithm for bisulfite sequencing using the Applied Biosystems SOLiD System
Summary: Bisulfite sequencing allows cytosine methylation, an important epigenetic marker, to be detected via nucleotide substitutions. Since the Applied Biosystems SOLiD System uses a unique di-base encoding that increases confidence in the detection of nucleotide substitutions, it is a potentially...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905549/ https://www.ncbi.nlm.nih.gov/pubmed/20562417 http://dx.doi.org/10.1093/bioinformatics/btq291 |