Human single-chain variable fragment that specifically targets arthritic cartilage

OBJECTIVE: To demonstrate that posttranslational modification of type II collagen (CII) by reactive oxygen species (ROS), which are known to be present in inflamed arthritic joints, can give rise to epitopes specific to damaged cartilage in rheumatoid arthritis (RA) and osteoarthritis (OA) and to es...

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Detalles Bibliográficos
Autores principales: Hughes, Chris, Faurholm, Bjarne, Dell'Accio, Francesco, Manzo, Antonio, Seed, Michael, Eltawil, Noha, Marrelli, Alessandra, Gould, David, Subang, Christina, Al-Kashi, Adam, De Bari, Cosimo, Winyard, Paul, Chernajovsky, Yuti, Nissim, Ahuva
Formato: Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
Materias:
Experimental Arthritis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905615/
https://www.ncbi.nlm.nih.gov/pubmed/20131274
http://dx.doi.org/10.1002/art.27346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905615/
https://www.ncbi.nlm.nih.gov/pubmed/20131274
http://dx.doi.org/10.1002/art.27346

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