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Metastatic Melanomas Express Inhibitory Low Affinity Fc Gamma Receptor and Escape Humoral Immunity

Our research, inspired by the pioneering works of Isaac Witz in the 1980s, established that 40% of human metastatic melanomas express ectopically inhibitory Fc gamma receptors (FcγRIIB), while they are detected on less than 5% of primary cutaneous melanoma and not on melanocytes. We demonstrated tha...

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Detalles Bibliográficos
Autores principales: Cohen-Solal, Joel F. G., Cassard, Lydie, Fournier, Emilie M., Loncar, Shannon M., Fridman, Wolf Herman, Sautès-Fridman, Catherine
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905727/
https://www.ncbi.nlm.nih.gov/pubmed/20672001
http://dx.doi.org/10.1155/2010/657406