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Conformational States and Kinetics of the Calcium Binding Domain of NADPH Oxidase 5

Superoxide generated by human NADPH oxidase 5 (NOX5) is of growing importance for various physiological and pathological processes. The activity of NOX5 appears to be regulated by a self-contained Ca(2+) binding domain (CaBD). Recently Bánfi et al. suggest that the conformational change of CaBD upon...

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Detalles Bibliográficos
Autores principales: Wei, Chin-Chuan, Motl, Nicole, Levek, Kelli, Chen, Liu Qi, Yang, Ya-Ping, Johnson, Tremylla, Hamilton, Lindsey, Stuehr, Dennis J
Formato: Texto
Lenguaje:English
Publicado: Bentham Open 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905766/
https://www.ncbi.nlm.nih.gov/pubmed/20648216
http://dx.doi.org/10.2174/1874091X01004010059