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Effects of Sitagliptin Treatment on Dysmetabolism, Inflammation, and Oxidative Stress in an Animal Model of Type 2 Diabetes (ZDF Rat)

The purpose of this paper is to evaluate the chronic effect of sitagliptin on metabolic profile, inflammation, and redox status in the Zucker Diabetic Fatty (ZDF) rat, an animal model of obese type 2 diabetes. Diabetic and obese ZDF (fa/fa) rats and their controls (ZDF +/+) were treated during 6 wee...

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Detalles Bibliográficos
Autores principales: Ferreira, Liliana, Teixeira-de-Lemos, Edite, Pinto, Filipa, Parada, Belmiro, Mega, Cristina, Vala, Helena, Pinto, Rui, Garrido, Patrícia, Sereno, José, Fernandes, Rosa, Santos, Paulo, Velada, Isabel, Melo, Andreia, Nunes, Sara, Teixeira, Frederico, Reis, Flávio
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905949/
https://www.ncbi.nlm.nih.gov/pubmed/20652060
http://dx.doi.org/10.1155/2010/592760