Elastase-mediated Activation of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein at Discrete Sites within the S2 Domain

Proteolytic priming is a common method of controlling the activation of membrane fusion mediated by viral glycoproteins. The severe acute respiratory syndrome coronavirus spike protein (SARS-CoV S) can be primed by a variety of host cell proteases, with proteolytic cleavage occurring both as the S1/...

Descripción completa

Detalles Bibliográficos
Autores principales: Belouzard, Sandrine, Madu, Ikenna, Whittaker, Gary R.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906266/
https://www.ncbi.nlm.nih.gov/pubmed/20507992
http://dx.doi.org/10.1074/jbc.M110.103275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906266/
https://www.ncbi.nlm.nih.gov/pubmed/20507992
http://dx.doi.org/10.1074/jbc.M110.103275

Ejemplares similares