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Membrane Trafficking of Large Conductance Calcium-activated Potassium Channels Is Regulated by Alternative Splicing of a Transplantable, Acidic Trafficking Motif in the RCK1-RCK2 Linker

Trafficking of the pore-forming α-subunits of large conductance calcium- and voltage-activated potassium (BK) channels to the cell surface represents an important regulatory step in controlling BK channel function. Here, we identify multiple trafficking signals within the intracellular RCK1-RCK2 lin...

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Detalles Bibliográficos
Autores principales: Chen, Lie, Jeffries, Owen, Rowe, Iain C. M., Liang, Zhi, Knaus, Hans-Guenther, Ruth, Peter, Shipston, Michael J.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906319/
https://www.ncbi.nlm.nih.gov/pubmed/20479001
http://dx.doi.org/10.1074/jbc.M110.139758