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An autocrine sphingosine-1-phosphate signaling loop enhances NF-κB-activation and survival
BACKGROUND: Sphingosine-1-phosphate (S1P) is a bioactive lipid that regulates a multitude of cellular functions, including cell proliferation, survival, migration and angiogenesis. S1P mediates its effects either by signaling through G protein-coupled receptors (GPCRs) or through an intracellular mo...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906432/ https://www.ncbi.nlm.nih.gov/pubmed/20573281 http://dx.doi.org/10.1186/1471-2121-11-45 |