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An autocrine sphingosine-1-phosphate signaling loop enhances NF-κB-activation and survival

BACKGROUND: Sphingosine-1-phosphate (S1P) is a bioactive lipid that regulates a multitude of cellular functions, including cell proliferation, survival, migration and angiogenesis. S1P mediates its effects either by signaling through G protein-coupled receptors (GPCRs) or through an intracellular mo...

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Detalles Bibliográficos
Autores principales:	Blom, Tomas, Bergelin, Nina, Meinander, Annika, Löf, Christoffer, Slotte, J Peter, Eriksson, John E, Törnquist, Kid
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906432/ https://www.ncbi.nlm.nih.gov/pubmed/20573281 http://dx.doi.org/10.1186/1471-2121-11-45

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