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Sodium butyrate enhances the cytotoxic effect of cisplatin by abrogating the cisplatin imposed cell cycle arrest

BACKGROUND: Histone deacetylase inhibitors have been proposed as potential enhancers of the cytotoxic effect of cisplatin and other anticancer drugs. Their application would permit the use of lower therapeutic doses and reduction of the adverse side effects of the drugs. However, the molecular mecha...

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Detalles Bibliográficos
Autores principales: Koprinarova, Miglena, Markovska, Petya, Iliev, Ivan, Anachkova, Boyka, Russev, George
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906439/
https://www.ncbi.nlm.nih.gov/pubmed/20576112
http://dx.doi.org/10.1186/1471-2199-11-49