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Computing and visually analyzing mutual information in molecular co-evolution

BACKGROUND: Selective pressure in molecular evolution leads to uneven distributions of amino acids and nucleotides. In fact one observes correlations among such constituents due to a large number of biophysical mechanisms (folding properties, electrostatics, ...). To quantify these correlations the...

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Detalles Bibliográficos
Autores principales: Bremm, Sebastian, Schreck, Tobias, Boba, Patrick, Held, Stephanie, Hamacher, Kay
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906490/
https://www.ncbi.nlm.nih.gov/pubmed/20565748
http://dx.doi.org/10.1186/1471-2105-11-330