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Predicting changes in protein thermostability brought about by single- or multi-site mutations
BACKGROUND: An important aspect of protein design is the ability to predict changes in protein thermostability arising from single- or multi-site mutations. Protein thermostability is reflected in the change in free energy (ΔΔG) of thermal denaturation. RESULTS: We have developed predictive software...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906492/ https://www.ncbi.nlm.nih.gov/pubmed/20598148 http://dx.doi.org/10.1186/1471-2105-11-370 |