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Thrombin-Activatable Fibrinolysis Inhibitor (TAFI) Deficient Mice Are Susceptible to Intracerebral Thrombosis and Ischemic Stroke

BACKGROUND: Thrombus formation is a key step in the pathophysiology of acute ischemic stroke and results from the activation of the coagulation cascade. Thrombin plays a central role in this coagulation system and contributes to thrombus stability via activation of thrombin-activatable fibrinolysis...

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Detalles Bibliográficos
Autores principales: Kraft, Peter, Schwarz, Tobias, Meijers, Joost C. M., Stoll, Guido, Kleinschnitz, Christoph
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906507/
https://www.ncbi.nlm.nih.gov/pubmed/20657835
http://dx.doi.org/10.1371/journal.pone.0011658