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Importance of Non-Selective Cation Channel TRPV4 Interaction with Cytoskeleton and Their Reciprocal Regulations in Cultured Cells

BACKGROUND: TRPV4 and the cellular cytoskeleton have each been reported to influence cellular mechanosensitive processes as well as the development of mechanical hyperalgesia. If and how TRPV4 interacts with the microtubule and actin cytoskeleton at a molecular and functional level is not known. MET...

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Detalles Bibliográficos
Autores principales: Goswami, Chandan, Kuhn, Julia, Heppenstall, Paul A., Hucho, Tim
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906515/
https://www.ncbi.nlm.nih.gov/pubmed/20657843
http://dx.doi.org/10.1371/journal.pone.0011654