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Autophagy is induced by adenoviral-mediated interferon α treatment in interferon resistant bladder cancer and normal urothelial cells as a cell death protective mechanism but not by the bystander factors produced
We have previously shown that adenoviral-mediated interferon α (Ad-IFNα) treatment is highly cytotoxic to tumor cells which are resistant to the interferon α̣ protein. We now report that autophagy is produced after Ad-IFNα treatment of either interferon resistant bladder cancer cells (UC-9 and KU7)...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906639/ https://www.ncbi.nlm.nih.gov/pubmed/20489789 http://dx.doi.org/10.1038/cgt.2010.14 |