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Autophagy is induced by adenoviral-mediated interferon α treatment in interferon resistant bladder cancer and normal urothelial cells as a cell death protective mechanism but not by the bystander factors produced

We have previously shown that adenoviral-mediated interferon α (Ad-IFNα) treatment is highly cytotoxic to tumor cells which are resistant to the interferon α̣ protein. We now report that autophagy is produced after Ad-IFNα treatment of either interferon resistant bladder cancer cells (UC-9 and KU7)...

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Detalles Bibliográficos
Autores principales: Zhang, Xin-Qiao, Dunner, Kenneth, Benedict, William F
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906639/
https://www.ncbi.nlm.nih.gov/pubmed/20489789
http://dx.doi.org/10.1038/cgt.2010.14