In vitro and in vivo multidrug resistance reversal activity by a Betti-base derivative of tylosin

BACKGROUND: The multidrug resistance (MDR) proteins are present in a majority of human tumours. Their activity is important to understand the chemotherapeutic failure. A search for MDR-reversing compounds was conducted among various Betti-base derivatives of tylosin. METHODS: Here, we evaluate the i...

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Detalles Bibliográficos
Autores principales: Gyémánt, N, Engi, H, Schelz, Z, Szatmári, I, Tóth, D, Fülöp, F, Molnár, J, de Witte, P A M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906729/
https://www.ncbi.nlm.nih.gov/pubmed/20551959
http://dx.doi.org/10.1038/sj.bjc.6605716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906729/
https://www.ncbi.nlm.nih.gov/pubmed/20551959
http://dx.doi.org/10.1038/sj.bjc.6605716

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