The tumour-suppressive miR-29a/b1 cluster is regulated by CEBPA and blocked in human AML

BACKGROUND: CCAAT/enhancer-binding protein-α (CEBPA) is crucial for normal granulopoiesis and is frequently disrupted in acute myeloid leukaemia (AML). Increasing evidence suggests that CEBPA exerts its effects, in parts, by regulating specific microRNAs (miRNAs), as previously shown for miR-223. Th...

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Detalles Bibliográficos
Autores principales: Eyholzer, M, Schmid, S, Wilkens, L, Mueller, B U, Pabst, T
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906742/
https://www.ncbi.nlm.nih.gov/pubmed/20628397
http://dx.doi.org/10.1038/sj.bjc.6605751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906742/
https://www.ncbi.nlm.nih.gov/pubmed/20628397
http://dx.doi.org/10.1038/sj.bjc.6605751

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