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The tumour-suppressive miR-29a/b1 cluster is regulated by CEBPA and blocked in human AML
BACKGROUND: CCAAT/enhancer-binding protein-α (CEBPA) is crucial for normal granulopoiesis and is frequently disrupted in acute myeloid leukaemia (AML). Increasing evidence suggests that CEBPA exerts its effects, in parts, by regulating specific microRNAs (miRNAs), as previously shown for miR-223. Th...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906742/ https://www.ncbi.nlm.nih.gov/pubmed/20628397 http://dx.doi.org/10.1038/sj.bjc.6605751 |