Common circuit defect of excitatory-inhibitory balance in mouse models of autism

One unifying explanation for the complexity of Autism Spectrum Disorders (ASD) may lie in the disruption of excitatory/inhibitory (E/I) circuit balance during critical periods of development. We examined whether Parvalbumin (PV)-positive inhibitory neurons, which normally drive experience-dependent...

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Detalles Bibliográficos
Autores principales: Gogolla, Nadine, LeBlanc, Jocelyn J., Quast, Kathleen B., Südhof, Thomas C., Fagiolini, Michela, Hensch, Takao K.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906812/
https://www.ncbi.nlm.nih.gov/pubmed/20664807
http://dx.doi.org/10.1007/s11689-009-9023-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906812/
https://www.ncbi.nlm.nih.gov/pubmed/20664807
http://dx.doi.org/10.1007/s11689-009-9023-x

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