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Common circuit defect of excitatory-inhibitory balance in mouse models of autism
One unifying explanation for the complexity of Autism Spectrum Disorders (ASD) may lie in the disruption of excitatory/inhibitory (E/I) circuit balance during critical periods of development. We examined whether Parvalbumin (PV)-positive inhibitory neurons, which normally drive experience-dependent...
Autores principales: | Gogolla, Nadine, LeBlanc, Jocelyn J., Quast, Kathleen B., Südhof, Thomas C., Fagiolini, Michela, Hensch, Takao K. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer US
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906812/ https://www.ncbi.nlm.nih.gov/pubmed/20664807 http://dx.doi.org/10.1007/s11689-009-9023-x |
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