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A Comparative Study of Age-Related Hearing Loss in Wild Type and Insulin-Like Growth Factor I Deficient Mice

Insulin-like growth factor-I (IGF-I) belongs to the family of insulin-related peptides that fulfils a key role during the late development of the nervous system. Human IGF1 mutations cause profound deafness, poor growth and mental retardation. Accordingly, Igf1(−/−) null mice are dwarfs that have lo...

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Detalles Bibliográficos
Autores principales: Riquelme, Raquel, Cediel, Rafael, Contreras, Julio, Lourdes, Rodriguez-de la Rosa, Murillo-Cuesta, Silvia, Hernandez-Sanchez, Catalina, Zubeldia, Jose M., Cerdan, Sebastian, Varela-Nieto, Isabel
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907134/
https://www.ncbi.nlm.nih.gov/pubmed/20661454
http://dx.doi.org/10.3389/fnana.2010.00027