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Nuclear localization of orphan receptor protein kinase (Ror1) is mediated through the juxtamembrane domain
BACKGROUND: Several receptor tyrosine kinases (RTKs) such as EGFR, FGFR, TRK, and VEGFR are capable of localizing in the cell nucleus in addition to their usual plasma membrane localization. Recent reports also demonstrate that nuclear-localized RTKs have important cellular functions such as transcr...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907318/ https://www.ncbi.nlm.nih.gov/pubmed/20587074 http://dx.doi.org/10.1186/1471-2121-11-48 |