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Nuclear localization of orphan receptor protein kinase (Ror1) is mediated through the juxtamembrane domain

BACKGROUND: Several receptor tyrosine kinases (RTKs) such as EGFR, FGFR, TRK, and VEGFR are capable of localizing in the cell nucleus in addition to their usual plasma membrane localization. Recent reports also demonstrate that nuclear-localized RTKs have important cellular functions such as transcr...

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Detalles Bibliográficos
Autores principales: Tseng, Hsiao-Chun, Lyu, Ping-Chiang, Lin, Wen-chang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907318/
https://www.ncbi.nlm.nih.gov/pubmed/20587074
http://dx.doi.org/10.1186/1471-2121-11-48