Cargando…

Nuclear localization of orphan receptor protein kinase (Ror1) is mediated through the juxtamembrane domain

BACKGROUND: Several receptor tyrosine kinases (RTKs) such as EGFR, FGFR, TRK, and VEGFR are capable of localizing in the cell nucleus in addition to their usual plasma membrane localization. Recent reports also demonstrate that nuclear-localized RTKs have important cellular functions such as transcr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tseng, Hsiao-Chun, Lyu, Ping-Chiang, Lin, Wen-chang
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907318/ https://www.ncbi.nlm.nih.gov/pubmed/20587074 http://dx.doi.org/10.1186/1471-2121-11-48

Ejemplares similares

Autoinhibition of the Ron receptor tyrosine kinase by the juxtamembrane domain
por: Wang, Xin, et al.
Publicado: (2014)

Crystal structure of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (hROR1)
por: Guarino, Salvatore R., et al.
Publicado: (2022)

Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain
por: Estevam, Gabriella O., et al.
Publicado: (2023)

Extracellular vesicle-associated tyrosine kinase-like orphan receptors ROR1 and ROR2 promote breast cancer progression
por: Irmer, Barnabas, et al.
Publicado: (2023)

The Orphan Tyrosine Kinase Receptor, ROR2, Mediates Wnt5A Signaling in Metastatic Melanoma
por: O’Connell, Michael P., et al.
Publicado: (2009)

The synaptotagmin juxtamembrane domain is involved in neuroexocytosis
por: Caccin, Paola, et al.
Publicado: (2015)

Meta-Analysis of Survival Effects of Receptor Tyrosine Kinase-like Orphan Receptor 1 (ROR1)
por: Jeong, Soo Young, et al.
Publicado: (2022)

ROR1: an orphan becomes apparent
por: Kipps, Thomas J.
Publicado: (2022)

Identification and validation of the pathways and functions regulated by the orphan nuclear receptor, ROR alpha1, in skeletal muscle
por: Raichur, S., et al.
Publicado: (2010)

Prognostic Value of the Expression of Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR-1) in Chronic Lymphocytic Leukemia
por: Yikilmaz, Aysun Şentürk, et al.
Publicado: (2023)

The nuclear retinoid‐related orphan receptor ROR α controls circadian thermogenic programming in white fat depots
por: Monnier, Chloé, et al.
Publicado: (2018)

Comparative Expression Profile of Orphan Receptor Tyrosine Kinase ROR1 in Iranian Patients with Lymphoid and Myeloid Leukemias
por: Shabani, Mahdi, et al.
Publicado: (2011)

ROR: Nuclear Receptor for Melatonin or Not?
por: Ma, Haozhen, et al.
Publicado: (2021)

Consequences of replacing EGFR juxtamembrane domain with an unstructured sequence
por: He, Lijuan, et al.
Publicado: (2012)

Tyrosine Phosphorylation of the BRI1 Receptor Kinase Occurs via a Post-Translational Modification and is Activated by the Juxtamembrane Domain
por: Oh, Man-Ho, et al.
Publicado: (2012)

Orphan Nuclear Receptor RORγ Modulates the Genome-Wide Binding of the Cholesterol Metabolic Genes during Mycotoxin-Induced Liver Injury
por: Li, Kaiqi, et al.
Publicado: (2021)

A putative pH-dependent nuclear localization signal in the juxtamembrane region of c-Met
por: Chaudhary, Shubhash Chandra, et al.
Publicado: (2014)

Retinoid orphan nuclear receptor alpha (RORα) suppresses the epithelial–mesenchymal transition (EMT) by directly repressing Snail transcription
por: Xiong, Gaofeng, et al.
Publicado: (2022)

Evolutionary Divergence in the Catalytic Activity of the CAM-1, ROR1 and ROR2 Kinase Domains
por: Bainbridge, Travis W., et al.
Publicado: (2014)

Orphan Nuclear Receptor RORα Regulates Enzymatic Metabolism of Cerebral 24S-Hydroxycholesterol through CYP39A1 Intronic Response Element Activation
por: Matsuoka, Hiroshi, et al.
Publicado: (2020)

Regulation of Expression of Citrate Synthase by the Retinoic Acid Receptor-Related Orphan Receptor α (RORα)
por: Crumbley, Christine, et al.
Publicado: (2012)

A Potential Peptide Therapeutic Derived from the Juxtamembrane Domain of the Epidermal Growth Factor Receptor
por: Boran, Aislyn D. W., et al.
Publicado: (2012)

Nuclear orphan receptor NR2F6 directly antagonizes NFAT and RORγt binding to the Il17a promoter
por: Hermann-Kleiter, Natascha, et al.
Publicado: (2012)

The juxtamembrane regions of human receptor tyrosine kinases exhibit conserved interaction sites with anionic lipids
por: Hedger, George, et al.
Publicado: (2015)

The Retinoid-Related Orphan Receptor RORα Promotes Keratinocyte Differentiation via FOXN1
por: Dai, Jun, et al.
Publicado: (2013)

Sleeping Beauty Transposition of Chimeric Antigen Receptors Targeting Receptor Tyrosine Kinase-Like Orphan Receptor-1 (ROR1) into Diverse Memory T-Cell Populations
por: Deniger, Drew C., et al.
Publicado: (2015)

Retinoid-related orphan receptors (RORs): critical roles in development, immunity, circadian rhythm, and cellular metabolism
por: Jetten, Anton M.
Publicado: (2009)

Retinoic Acid-Related Orphan Receptors (RORs): Regulatory Functions in Immunity, Development, Circadian Rhythm, and Metabolism
por: Cook, Donald N., et al.
Publicado: (2015)

Fusion with wild-type SNARE domains is controlled by juxtamembrane domains, transmembrane anchors, and Sec17
por: Orr, Amy, et al.
Publicado: (2022)

RAR‐Related Orphan Receptor Gamma (ROR‐γ) Mediates Epithelial‐Mesenchymal Transition Of Hepatocytes During Hepatic Fibrosis
por: Kim, Sung Min, et al.
Publicado: (2017)

The architecture of transmembrane and cytoplasmic juxtamembrane regions of Toll-like receptors
por: Kornilov, F. D., et al.
Publicado: (2023)

Ligand-Based Design of Allosteric Retinoic Acid Receptor-Related Orphan Receptor γt (RORγt) Inverse Agonists
por: Meijer, Femke A., et al.
Publicado: (2019)

Role for Retinoic Acid-Related Orphan Receptor Alpha (RORα) Expressing Macrophages in Diet-Induced Obesity
por: Hams, Emily, et al.
Publicado: (2020)

c-Met Mutational Analysis in the Sema and Juxtamembrane Domains in Small-Cell-Lung-Cancer
por: de Aguirre, Itziar, et al.
Publicado: (2006)

The juxtamembrane domain of the E-cadherin cytoplasmic tail contributes to its interaction with Myosin VI
por: Mangold, Sabine, et al.
Publicado: (2012)

The first non Clostridial botulinum-like toxin cleaves VAMP within the juxtamembrane domain
por: Zornetta, Irene, et al.
Publicado: (2016)

An autoregulatory loop controlling orphan nuclear receptor DAX-1 gene expression by orphan nuclear receptor ERRγ
por: Park, Yun-Yong, et al.
Publicado: (2005)

An autoregulatory loop controlling orphan nuclear receptor DAX-1 gene expression by orphan nuclear receptor ERRγ
por: Park, Yun-Yong, et al.
Publicado: (2018)

An autoregulatory loop controlling orphan nuclear receptor DAX-1 gene expression by orphan nuclear receptor ERRγ
por: Park, Yun-Yong, et al.
Publicado: (2019)

Deletion and deletion/insertion mutations in the juxtamembrane domain of the FLT3 gene in adult acute myeloid leukemia
por: Deeb, Kristin K., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_vet9pl9d43rrf527j5h310u6vn