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Effects of small interfering RNAs targeting fascin on human esophageal squamous cell carcinoma cell lines

BACKGROUND: Fascin induces membrane protrusions and cell motility. Fascin overexpression was associated with poor prognosis, and its downregulation reduces cell motility and invasiveness in esophageal squamous cell carcinoma (ESCC). Using a stable knockdown cell line, we revealed the effect of fasci...

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Detalles Bibliográficos
Autores principales: Ortiz, Cristian M, Ito, Tetsuo, Hashimoto, Yosuke, Nagayama, Satoshi, Iwai, Akira, Tsunoda, Shigeru, Sato, Fumiaki, Martorell, Miguel, Garcia, Jose Angel, Perez, Ana, Shimada, Yutaka
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907320/
https://www.ncbi.nlm.nih.gov/pubmed/20565981
http://dx.doi.org/10.1186/1746-1596-5-41