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Undetected antisense tRNAs in mitochondrial genomes?

BACKGROUND: The hypothesis that both mitochondrial (mt) complementary DNA strands of tRNA genes code for tRNAs (sense-antisense coding) is explored. This could explain why mt tRNA mutations are 6.5 times more frequently pathogenic than in other mt sequences. Antisense tRNA expression is plausible be...

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Detalles Bibliográficos
Autor principal: Seligmann, Hervé
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907346/
https://www.ncbi.nlm.nih.gov/pubmed/20553583
http://dx.doi.org/10.1186/1745-6150-5-39