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LRP5 Is Required for Vascular Development in Deeper Layers of the Retina
BACKGROUND: The low-density lipoprotein receptor-related protein 5 (LRP5) plays an important role in the development of retinal vasculature. LRP5 loss-of-function mutations cause incomplete development of retinal vessel network in humans as well as in mice. To understand the underlying mechanism for...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907392/ https://www.ncbi.nlm.nih.gov/pubmed/20652025 http://dx.doi.org/10.1371/journal.pone.0011676 |