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Reduced Body Weight and Increased Energy Expenditure in Transgenic Mice Over-Expressing Soluble Leptin Receptor

BACKGROUND: Soluble leptin receptor (OBRe), one of several leptin receptor isoforms, is the only bona fide leptin binding protein in plasma. Our earlier studies demonstrated that OBRe modulates leptin levels in circulation. Both clinical and in vitro studies have shown that OBRe expression is invers...

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Detalles Bibliográficos
Autores principales: Lou, Phing-How, Yang, Guoqing, Huang, Lu, Cui, Yunxia, Pourbahrami, Tiffany, Radda, George K., Li, Cai, Han, Weiping
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907393/
https://www.ncbi.nlm.nih.gov/pubmed/20652026
http://dx.doi.org/10.1371/journal.pone.0011669