Protection of Macaques with Diverse MHC Genotypes against a Heterologous SIV by Vaccination with a Deglycosylated Live-Attenuated SIV

HIV vaccine development has been hampered by issues such as undefined correlates of protection and extensive diversity of HIV. We addressed these issues using a previously established SIV-macaque model in which SIV mutants with deletions of multiple gp120 N-glycans function as potent live attenuated...

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Detalles Bibliográficos
Autores principales: Sugimoto, Chie, Watanabe, Satoru, Naruse, Taeko, Kajiwara, Eiji, Shiino, Teiichiro, Umano, Natsuko, Ueda, Kayoko, Sato, Hirotaka, Ohgimoto, Shinji, Hirsch, Vanessa, Villinger, Francois, Ansari, Aftab A., Kimura, Akinori, Miyazawa, Masaaki, Suzuki, Yasuo, Yamamoto, Naoki, Nagai, Yoshiyuki, Mori, Kazuyasu
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907403/
https://www.ncbi.nlm.nih.gov/pubmed/20652030
http://dx.doi.org/10.1371/journal.pone.0011678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907403/
https://www.ncbi.nlm.nih.gov/pubmed/20652030
http://dx.doi.org/10.1371/journal.pone.0011678

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