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A poxvirus Bcl-2-like gene family involved in regulation of host immune response: sequence similarity and evolutionary history

BACKGROUND: Poxviruses evade the immune system of the host through the action of viral encoded inhibitors that block various signalling pathways. The exact number of viral inhibitors is not yet known. Several members of the vaccinia virus A46 and N1 families, with a Bcl-2-like structure, are involve...

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Detalles Bibliográficos
Autores principales: González, José M, Esteban, Mariano
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907574/
https://www.ncbi.nlm.nih.gov/pubmed/20230632
http://dx.doi.org/10.1186/1743-422X-7-59