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Oncolytic measles viruses encoding interferon β and the thyroidal sodium iodide symporter gene for mesothelioma virotherapy

Mesothelioma usually leads to death within 8–14 months of diagnosis. To increase the potency of oncolytic measles viruses (MVs) for mesothelioma therapy, we inserted the interferon β (IFNβ) gene alone or with the human thyroidal sodium iodide symporter (NIS) gene into attenuated MV of the Edmonston...

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Detalles Bibliográficos
Autores principales: Li, H, Peng, K-W, Dingli, D, Kratzke, R A, Russell, S J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907639/
https://www.ncbi.nlm.nih.gov/pubmed/20379224
http://dx.doi.org/10.1038/cgt.2010.10