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Relationship between estrogen receptor α location and gene induction reveals the importance of downstream sites and cofactors

BACKGROUND: To understand cancer-related modifications to transcriptional programs requires detailed knowledge about the activation of signal-transduction pathways and gene expression programs. To investigate the mechanisms of target gene regulation by human estrogen receptor α (hERα), we combine ex...

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Detalles Bibliográficos
Autores principales: Parisi, Fabio, Sonderegger, Bernhard, Wirapati, Pratyaksha, Delorenzi, Mauro, Naef, Felix
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907696/
https://www.ncbi.nlm.nih.gov/pubmed/19689805
http://dx.doi.org/10.1186/1471-2164-10-381