The potency of the fs260 connexin43 mutant to impair keratinocyte differentiation is distinct from other disease-linked connexin43 mutants

Although there are currently 62 mutants of Cx43 (connexin43) that can cause ODDD (oculodentodigital dysplasia), only two mutants have also been reported to cause palmar plantar hyperkeratosis. To determine how mutants of Cx43 can lead to this skin disease, REKs (rat epidermal keratinocytes) were eng...

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Detalles Bibliográficos
Autores principales: Churko, Jared M., Langlois, Stephanie, Pan, Xinyue, Shao, Qing, Laird, Dale W.
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907710/
https://www.ncbi.nlm.nih.gov/pubmed/20515445
http://dx.doi.org/10.1042/BJ20100155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907710/
https://www.ncbi.nlm.nih.gov/pubmed/20515445
http://dx.doi.org/10.1042/BJ20100155

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