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Propagation of kinetic uncertainties through a canonical topology of the TLR4 signaling network in different regions of biochemical reaction space

BACKGROUND: Signal transduction networks represent the information processing systems that dictate which dynamical regimes of biochemical activity can be accessible to a cell under certain circumstances. One of the major concerns in molecular systems biology is centered on the elucidation of the rob...

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Detalles Bibliográficos
Autores principales: Gutiérrez, Jayson, St Laurent, Georges, Urcuqui-Inchima, Silvio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907738/
https://www.ncbi.nlm.nih.gov/pubmed/20230643
http://dx.doi.org/10.1186/1742-4682-7-7