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Development of clinically relevant orthotopic xenograft mouse model of metastatic lung cancer and glioblastoma through surgical tumor tissues injection with trocar

OBJECTIVE: Orthotopic models are important in cancer research. Here we developed orthotopic xenograft mouse model of metastatic lung cancer and glioblastoma with a specially designed system. METHODS: Tiny fragments of surgical tumors were implanted into the mice brain with a trocar system. Immunohis...

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Detalles Bibliográficos
Autores principales: Fei, Xi Feng, Zhang, Quan Bin, Dong, Jun, Diao, Yi, Wang, Zhi Min, Li, Ru Jun, Wu, Zi Cheng, Wang, Ai Dong, Lan, Qing, Zhang, Shi Ming, Huang, Qiang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907866/
https://www.ncbi.nlm.nih.gov/pubmed/20587035
http://dx.doi.org/10.1186/1756-9966-29-84