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Heritability in the Efficiency of Nonsense-Mediated mRNA Decay in Humans
BACKGROUND: In eukaryotes mRNA transcripts of protein-coding genes in which an intron has been retained in the coding region normally result in premature stop codons and are therefore degraded through the nonsense-mediated mRNA decay (NMD) pathway. There is evidence in the form of selective pressure...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908117/ https://www.ncbi.nlm.nih.gov/pubmed/20657766 http://dx.doi.org/10.1371/journal.pone.0011657 |