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A Gammaherpesvirus Complement Regulatory Protein Promotes Initiation of Infection by Activation of Protein Kinase Akt/PKB

BACKGROUND: Viruses have evolved to evade the host's complement system. The open reading frames 4 (ORF4) of gammaherpesviruses encode homologs of regulators of complement activation (RCA) proteins, which inhibit complement activation at the level of C3 and C4 deposition. Besides complement regu...

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Detalles Bibliográficos
Autores principales: Steer, Beatrix, Adler, Barbara, Jonjic, Stipan, Stewart, James P., Adler, Heiko
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908122/
https://www.ncbi.nlm.nih.gov/pubmed/20657771
http://dx.doi.org/10.1371/journal.pone.0011672