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A Gammaherpesvirus Complement Regulatory Protein Promotes Initiation of Infection by Activation of Protein Kinase Akt/PKB
BACKGROUND: Viruses have evolved to evade the host's complement system. The open reading frames 4 (ORF4) of gammaherpesviruses encode homologs of regulators of complement activation (RCA) proteins, which inhibit complement activation at the level of C3 and C4 deposition. Besides complement regu...
Autores principales: | Steer, Beatrix, Adler, Barbara, Jonjic, Stipan, Stewart, James P., Adler, Heiko |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908122/ https://www.ncbi.nlm.nih.gov/pubmed/20657771 http://dx.doi.org/10.1371/journal.pone.0011672 |
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